The Importance of Beta-hCG and Double Marker Test

A woman’s body changes a lot during pregnancy. Prenatal screening and tests are more than just routine procedures; they are valuable tools that provide crucial information about the mother's and baby’s health. Prenatal tests help doctors monitor pregnancy at every critical stage to understand foetal development and detect any potential health concerns early on. Two of the main tests conducted during these 9 months are beta-hCG and the double marker tests. 

Beta-hCG 

The beta-hCG test is one of the earliest blood tests done during pregnancy. Beta-hCG tests for the presence of human chorionic gonadotropin (hCG) hormone, which is produced by the placenta. hCG levels rise quickly, very early in healthy pregnancies. 

This quantitative test determines the precise concentration of hCG in the blood. Beta-hCG not only confirms pregnancy but, when monitored over time, can also provide valuable clues about the early progression of the pregnancy and help identify potential risks like ectopic pregnancy or miscarriage. However, an ultrasound is the primary method for accurately determining gestational age and assessing detailed fetal development. 

What hCG Levels Mean?

hCG levels typically peak around 8-11 weeks of gestation. After reaching this peak, they tend to decrease and then remain stable at a lower level for the rest of the pregnancy. 

• Higher than expected levels can be a sign of multiple pregnancies, molar pregnancy or gestational trophoblastic disease. 

• Low hCG levels early in the pregnancy can indicate an increased risk of miscarriage, ectopic pregnancy or anembryonic pregnancy.

  
  
  
  

While Beta-hCG testing is helpful, it’s important to know that hCG levels are not conclusive of a condition. Ongoing health conditions, medication, sample handling and laboratory standards can influence the test results. Doctors may recommend further testing.

Double Marker Test

The double marker test for pregnancy is done during the first trimester. It is a crucial screening test that assesses the placental health through specific biomarkers like free beta-hCG and PAPP-A (Pregnancy-Associated Plasma Protein-A). The test is useful for screening for potential health concerns, particularly Down syndrome (Trisomy 21), Edward syndrome (Trisomy 18), and Patau syndrome (Trisomy 13). 

Understanding Double Marker Test Results

A result like 1:1000 indicates a low risk of chromosomal abnormalities. This means that for every 1000 pregnancies with this result, statistically, only 1 is expected to have the condition. Conversely, a higher risk result (e.g., 1:100 or 1:50) would suggest a greater chance that the baby might have the abnormality, prompting further diagnostic testing.

The Double Marker Test, which utilises biomarkers like free beta-hCG, is a crucial part of early screening for chromosomal abnormalities. Together with other prenatal assessments, these tests provide valuable information that can help prepare parents and doctors to provide appropriate care if needed.

Before scheduling your tests, you may want to explore the Full Body Checkup Price in Chennai to choose an option that matches your health goals.